The St. Regis Venice San Clemente Palace.
ITALIAN ESCAPE The St. Regis Venice San Clemente Palace debuts in April on a private island in the center of the city’s lagoon. Housed in a former monastery, the property’s 191 guest rooms and suites were restored and redesigned by Hirsch Bedner Associates and GA Design. A private boat service connects guests to the city’s many attractions (which include the requisite gondola ride). From $625, including breakfast. stregis.com
ZEN SANCTUARY Perched on the top six floors of a high-rise in the financial district, the new Aman Tokyo marries traditional Japanese design with modern style. Designed by Kerry Hill Architects, the 84-room property boasts three restaurants, a swimming pool and a sprawling wellness facility with dramatic views of the city skyline. Rates from $630. amanresorts.com
MODERN RETREAT Designed by GCA Architects Associates, Barcelona’s ABaC Restaurant & Hotel encompasses a new building integrated with a former home that historically served as the American Embassy in Spain. Today the 15-room property boasts sleek, modern guest suites with Bang & Olufsen TVs and sound systems and Hermès toiletries, a spa and a lounge adjoining a restaurant with two Michelin stars. Rates from $244. abacbarcelona.com